TY  - ADVS
AU  - Hubbard,Stevan R.
TI  - Structure and mechanism of the tyrosine kinase domain of the insulin receptor
T2  - Signal transduction via protein tyrosine kinase receptors : structures, function, regulation, mechanisms and role in disease,
PY  - 2007///
CY  - London
PB  - Henry Stewart Talks
KW  - Protein-Tyrosine Kinases
KW  - Receptor Protein-Tyrosine Kinases
KW  - Receptor, Insulin
KW  - Signal Transduction
N1  - Animated audio-visual presentation with synchronized narration; Title from title frames; Contents: Introduction to receptor tyrosine kinases (RTKs) -- general mechanisms of protein recruitment to RTKs -- Structure of the insulin receptor tyrosine kinase domain (IRK) -- Autoinhibitory mechanisms in RTKs -- Structure of the Src homology-2 (SH2) domain of APS -- Structure of the APS SH2 domain bound to IRK -- Inhibition of IRK activity by Grb14 -- Structure of the Grb14 BPS region bound to IRK -- Structure of the Grb14 SH2 domain -- Model of the interaction between Grb14 and the insulin receptor; Access restricted to subscribers
UR  - https://hstalks.com/bs/454/
UR  - https://hstalks.com/bs/p/38/
ER  -