TY  - ADVS
AU  - Lyon,Mary F.
TI  - A historical perspective on ideas on X-chromosome inactivation
T2  - Epigenetics : concepts, theories, paradigms and mechanisms,
PY  - 2007///
CY  - London
PB  - Henry Stewart Talks
KW  - Epigenesis, Genetic
KW  - X Chromosome Inactivation
N1  - Animated audio-visual presentation with synchronized narration; Title from title frames; Contents: The phenomenon of X-chromosome inactivation in female mammals -- X-chromosome inactivation as a dosage compensation mechanism for equalising the dosage of X-linked gene products in XY males and XX females in somatic cells -- inactivity of either the maternal or paternal X-chromosome in different cells in eutherian mammals -- preferential inactivation of paternal X in the placenta of mice and in all cells of marsupials -- initiation of the process from an X-inactivation centre -- discovery of the key gene, Xist -- the concept of initiation and maintenance of X-inactivation as separate processes -- histone modifications and methylation of CpG islands as maintenance mechanisms -- inactivation in autosomal and X-chromosomal DNA -- LINE1s as booster elements on the X-chromosome; Access restricted to subscribers
UR  - https://hstalks.com/bs/107/
UR  - https://hstalks.com/bs/p/18/
ER  -