TY - ADVS AU - Butt,Mark T. TI - Evaluation of the adult nervous system in preclinical studies T2 - Non-clinical testing for toxicity of pharmaceuticals : regulatory and practical standards for testing and application, PY - 2009/// CY - London PB - Henry Stewart Talks KW - Drug Toxicity KW - Toxicity Tests N1 - Animated audio-visual presentation with synchonized narration; Title from title frames; Contents: Brain is a heterogeneous tissue: you must look at many sections -- Different toxicants affect different areas -- Timing is important but most cell death occurs early (1 to 4 days) -- Appropriate fixation is crucial -- Appropriate staining methods are necessary to detect changes in various cell types (neurons, glial cells); Access restricted to subscribers UR - https://hstalks.com/bs/1348/ UR - https://hstalks.com/bs/p/438/ ER -