TY - ADVS AU - Afshari,Cindy TI - Introduction to toxicogenomics and example case studies T2 - Non-clinical testing for toxicity of pharmaceuticals : regulatory and practical standards for testing and application, PY - 2009/// CY - London PB - Henry Stewart Talks KW - Drug Toxicity KW - Toxicity Tests N1 - Animated audio-visual presentation with synchonized narration; Title from title frames; Contents: What is toxicogenomics and what is it not? -- General considerations -- Compound discrimination -- Pathway modeling -- Modulation of the notch pathway -- Altered transcripts -- Understand compound mechanism of action -- Case study: hepatotoxicity -- For the future: translation; Access restricted to subscribers UR - https://hstalks.com/bs/1350/ UR - https://hstalks.com/bs/p/438/ ER -