TY - ADVS AU - Conrad,Donald TI - Population genetics of structural variation T2 - Copy number variation : expanding the repertoire of genetic alterations in studies of natural variation and disease, PY - 2009/// CY - London PB - Henry Stewart Talks KW - Gene Dosage KW - Genetic Variation KW - Genetics, Population KW - Genome, Human N1 - Animated audio-visual presentation with synchonized narration; Title from title frames; Contents: Importance of ascertainment -- Mutation processes, rates and mutation rate modifiers -- Interplay between structural variation and recombination and gene conversion -- Distribution of structural variants within and between human populations -- Shared patterns of SV polymorphism among species -- Functional constraint on CNVs -- Evidence for positive selection on CNVs; Access restricted to subscribers UR - https://hstalks.com/bs/1396/ UR - https://hstalks.com/bs/p/439/ ER -