TY - ADVS AU - Lanier,Lewis L. TI - NK cells in viral immunity T2 - Natural killer cell biology : natural killer cell-mediated immunity to pathogens and cancer, PY - 2009/// CY - London PB - Henry Stewart Talks KW - Cytotoxicity, Immunologic KW - Killer Cells, Natural KW - Neoplasms N1 - Animated audio-visual presentation with synchonized narration; Title from title frames; Contents: Why do we have NK cells? -- Importance in viral immunity -- NK cell responses to interferon alpha/beta and cytokines induced by virus -- Control of replication in viruses -- Mouse cytomegalovirus (MCMV) -- Ly49 receptors -- Inhibitory and activating Ly49 receptors -- Direct recognition of virus-infected cells by NK cells -- Ly49H is the receptor for m157 MCMV glycoprotein -- Why did m157 evolve and why is it maintained? -- Ly49 genes are polymorphic -- Virus-driven NK receptor evolution -- Is Ly49H an exception or do other activating Ly49 receptors protect against MCMV? -- Direct recognition of virus-infected cells by NK cells -- NK cells and cytomegalovirus -- NK cells and poxviruses -- Natural cytotoxicity receptors -- NK cells in human viral immunity -- Association of KIR genes with viral infection; Access restricted to subscribers UR - https://hstalks.com/bs/1456/ UR - https://hstalks.com/bs/p/440/ ER -