TY - ADVS AU - Barford,David TI - Structure and mechanisms of protein phosphatases T2 - Protein phosphorylation, PY - 2010/// CY - London PB - Henry Stewart Talks KW - Phosphoprotein Phosphatases KW - Phosphorylation KW - Protein Tyrosine Phosphatases N1 - Animated audio-visual presentation with synchronized narration; Title from title frames; Contents: Reversible protein phosphorylation -- Classification of protein phosphatases -- Protein tyrosine phosphatase family, structure of PTP1B, catalytic mechanism, basis for pTyr specificity, recognition of IRK, regulation by ROS and cyclic sulphenamide -- Dual specificity phosphatases -- Eya protein tyrosine phosphatases -- PPP family of Ser/Thr phosphatases, structure of PP1, catalytic mechanism, inhibition by okadaic acid and microcystin, targeting subunits, PP2A, PP2B, PP5 -- PPM family of Ser/Thr phosphatases, structure, catalytic mechanism -- Summary; Access restricted to subscribers UR - https://hstalks.com/bs/1883/ UR - https://hstalks.com/bs/p/531/ ER -