TY  - ADVS
AU  - Alessi,Dario
TI  - WNK1 pathway and its role in regulating hypertension
T2  - Protein phosphorylation,
PY  - 2011///
CY  - London
PB  - Henry Stewart Talks
KW  - Hypertension
KW  - Phosphorylation
KW  - Protein Kinases
N1  - Animated audio-visual presentation with synchronized narration; Title from title frames; Contents: Mutations in WNK kinases cause familial hypertension -- WNK1 interacts with and activates SPAK and OSR1 -- Physiological functions of SPAK and OSR1 -- Hyperosmotic conditions affect NKCC1 via WNK1 and SPAK/OSR1 -- A suggested mechanism of action for Thiazide diuretics in Gordon's syndrome patients -- How the WNK pathway regulates blood pressure-a current model -- Defining physiological roles of SPAK in knock-in mice -- MO25 also regulates the activity of SPAK/OSR1 -- Functions and schematic representation of LKB1 and SPAK/OSR1 protein complexes; Access restricted to subscribers
UR  - https://hstalks.com/bs/1974/
UR  - https://hstalks.com/bs/p/531/
ER  -