TY  - ADVS
AU  - Alessi,Dario
TI  - LKB1 pathway and its role in cancer
T2  - Protein phosphorylation,
PY  - 2011///
CY  - London
PB  - Henry Stewart Talks
KW  - Neoplasms
KW  - Phosphorylation
KW  - Protein Kinases
N1  - Animated audio-visual presentation with synchronized narration; Title from title frames; Contents: Mutations in LKB1 kinase cause Peutz Jeghers cancer syndrome -- LKB1-activation and effects -- LKB1/AMPK signaling pathway inhibits mTOR -- Evaluating the role of LKB1 in regulating PTEN-induced tumourigenesis -- AMPK-activators-mechanisms of action -- AMPK-activators delay tumor onset in mice -- Metformin as a useful drug in cancer prevention -- The LKB1:STRAD:MO25 complex -- Potential evolution of a pseudokinase -- LKB activation by STRAD and MO25 -- Location of LKB1 cancer mutations -- Activating protein kinases as a key challenge -- Analysis of the NUAK protein kinase -- Studying the role LKB1/NUAK1 signaling pathway in regulating cell adhesiveness and migration -- Modeling the novel LKB1; Access restricted to subscribers
UR  - https://hstalks.com/bs/1975/
UR  - https://hstalks.com/bs/p/531/
ER  -