TY - ADVS AU - Svanborg,Catharina TI - Innate immunity in the genitourinary tract: genetics of susceptibility to disease or asymptomatic carriage T2 - Cells of the innate immune system : roles in health and disease, PY - 2012/// CY - London PB - Henry Stewart Talks KW - Host-bacteria relationships KW - Natural immunity KW - Urinary tract infections KW - Immunology KW - Bacteriuria KW - immunology KW - Genetic Predisposition to Disease KW - genetics KW - Host-Pathogen Interactions KW - Immunity, Innate KW - Signal Transduction KW - Urinary Tract Infections N1 - Animated audio-visual presentation with synchronized narration; Title from title frames; Contents: Pathogens\Commensals at the mucosal level -- How pathogenic bacteria activate a host response -- Pathogen specific innate immune signaling -- Urinary tract infections (UTI) -- Uropathogenic E. coli vs. ABU strains -- TLR4, CXCR1, IRF3, IL8R role in UTI response -- Importance of identifying signaling pathways & crucial effector cells -- Acute/Chronic pyelonephritis & asymptomatic bacteriuria -- Genetics & UTI -- Researching disease-associated polymorphisms -- SNPs and their effect in APN & UTI -- Mutations in structural genes -- Response to infection in reporter assays -- Commensalism vs. Virulence; Access restricted to subscribers UR - https://hstalks.com/bs/2287/ UR - https://hstalks.com/bs/p/667/ ER -