TY - ADVS AU - Van Petegem,Filip TI - Disease hot spots of ryanodine receptors T2 - Calcium signaling II : calcium and disease, PY - 2012/// CY - London PB - Henry Stewart Talks KW - Arrhythmia KW - Malignant Hyperthermia KW - Ryanodine KW - Receptors KW - Arrhythmias, Cardiac KW - Ryanodine Receptor Calcium Release Channel KW - genetics KW - metabolism N1 - Animated audio-visual presentation with synchronized narration; Title from title frames; Contents: Ryanodine Receptors and calcium release -- Disease mutations: malignant hyperthermia and cardiac arrhythmia -- Disease hot spots and their locations -- High Resolution structures: mutations and domain interfaces -- deletion of exon3 -- Common allosteric mechanisms in IP3 receptors; Access restricted to subscribers UR - https://hstalks.com/bs/2407/ UR - https://hstalks.com/bs/p/683/ ER -