TY  - ADVS
AU  - Whitty,Adrian
TI  - Inhibiting protein-protein interactions: part 2 of 2 
T2  - Small molecule drug discovery,
PY  - 2014///
CY  - London
PB  - Henry Stewart Talks
KW  - Drug development
KW  - Drug targeting
KW  - Protein-protein interactions
KW  - Proteins
KW  - Inhibitors
KW  - Drug Design
KW  - Drug Discovery
KW  - Protein Binding
KW  - drug effects
KW  - Protein Interaction Mapping
KW  - antagonists & inhibitors
KW  - metabolism
KW  - Small Molecule Libraries
KW  - pharmacology
N1  - Animated audio-visual presentation with synchronized narration; Title from title frames; Contents: A different view of druggability -- Five propositions about the druggability of PPI targets -- Protein-ligand binding energy -- Ligand efficiency and drug-target binding -- ADME & druglikeness considerations -- Conventional view of druglikeness -- Druggability and chemical space -- Targeting low druggability PPI -- Macrocycles -- Covalent inhibitors -- Foldamers; Access restricted to subscribers
UR  - https://hstalks.com/bs/2776/
UR  - https://hstalks.com/bs/p/739/
ER  -