TY - ADVS AU - De Silva,Rohan TI - The genetics of progressive supranuclear palsy (PSP) and corticobasal degeneration (CBD) T2 - The genetic basis of neurological disorders, PY - 2014/// CY - London PB - Henry Stewart Talks KW - Nervous system KW - Degeneration KW - Genetic aspects KW - Diseases KW - Progressive supranuclear palsy KW - Neurodegenerative Diseases KW - genetics KW - Supranuclear Palsy, Progressive N1 - Animated audio-visual presentation with synchronized narration; Title from title frames; Contents: PSP and CBD -- Genetic risk versus inherited gene defects -- tauopathies -- tau pathology -- Role and dysfunction of tau -- tau gene expression and splicing -- Inherited tau mutations and frontotemporal dementia -- the tau gene H1 haplotype -- Functional basis of association of H1 with neurodegeneration -- Antiphospholipid antibodies and atherosclerosis -- Other genetic associations implicating myelination and white matter changes and endoplasmic reticulum stress response; Access restricted to subscribers UR - https://hstalks.com/bs/2845/ UR - https://hstalks.com/bs/p/908/ ER -