TY - ADVS AU - Gabrilovich,Dmitry I. TI - Immunosuppressive mechanisms in myeloid cells T2 - Immunotherapy of cancer, PY - 2014/// CY - London PB - Henry Stewart Talks KW - Immunosuppression KW - T cells KW - Tumors KW - Immunological aspects KW - Immune Tolerance KW - Immunosuppressive Agents KW - immunology KW - Myeloid Cells KW - metabolism KW - Neoplasms KW - T-Lymphocytes N1 - Animated audio-visual presentation with synchronized narration; Title from title frames; Contents: Myeloid derived suppressor cells (MDSC) and their potent immune suppressive activity -- MDSC in cancer -- MDSC in chronic infections -- MDSC during stress -- MDSC in surgical trauma -- The two main populations of MDSC: monocytic MDSC (M-MDSC) and polymorphonuclear MDSC (PMN-MDSC) -- Biological differences between MDSC and their normal counterparts -- Multiple mechanisms of expansion regulation and immune suppressive function of MDSC -- MDSC role in antigen-specific T cell tolerance in tumor-bearing mice -- Therapeutic regulation of MDSC in mice and humans; Access restricted to subscribers UR - https://hstalks.com/bs/2956/ UR - https://hstalks.com/bs/p/668/ UR - https://hstalks.com/bs/p/896/ ER -