TY  - ADVS
AU  - Dean,Ann
TI  - The Beta-globin locus
T2  - Epigenetics, chromatin, transcription and cancer,
PY  - 2014///
CY  - London
PB  - Henry Stewart Talks
KW  - Epigenesis
KW  - Genetic regulation
KW  - Genetic transcription
KW  - Regulation
KW  - Hemoglobin
KW  - Sickle cell anemia
KW  - Anemia, Sickle Cell
KW  - genetics
KW  - beta-Globins
KW  - beta-Thalassemia
KW  - Cell Nucleus
KW  - metabolism
KW  - Chromatin
KW  - Chromosome Structures
KW  - Epigenesis, Genetic
KW  - Erythroid Cells
KW  - Eukaryotic Cells
KW  - Gene Expression Regulation
KW  - Genetic Loci
KW  - Hemoglobin Subunits
KW  - Hemoglobins
KW  - Transcription Factors
KW  - physiology
KW  - Transcription, Genetic
N1  - Animated audio-visual presentation with synchronized narration; Title from title frames; Updated version of a talk first published in 2007; Contents: The globin loci encode hemoglobin subunits -- Erythrocytes & hemoglobin -- Human globin genes and hemoglobins -- Globin gene expression during development -- Globin gene structure -- Sickle cell disease -- Beta-thalassemia -- Transcriptional regulation by recruitment (Enhancers, Silencers and Insulators) -- Chromatin conformation capture (3C) assay -- Chromatin looping in the beta-globin locus -- The LDB1 complex in erythroid cells -- Nuclear re-location of the beta-globin locus -- Natural mutations and hemoglobin switching  -- BCL11A, beta-globin and gamma-globin expression -- Interfering with BCL11A silencing; Access restricted to subscribers
UR  - https://hstalks.com/bs/673/
UR  - https://hstalks.com/bs/p/19/
UR  - https://hstalks.com/bs/p/685/
ER  -