TY - ADVS AU - Brockdorff,Neil TI - The molecular mechanism of X chromosome inactivation T2 - Epigenetics : concepts, theories, paradigms and mechanisms, PY - 2016/// CY - London PB - Henry Stewart Talks KW - Chromatin KW - Epigenesis KW - Gene expression KW - Gene silencing KW - Genetic regulation KW - Molecular genetics KW - Non-coding RNA KW - X chromosome KW - genetics KW - metabolism KW - Epigenesis, Genetic KW - Gene Expression Regulation, Developmental KW - Gene Silencing KW - Mice KW - Models, Biological KW - Mosaicism KW - RNA, Long Noncoding KW - X Chromosome Inactivation KW - physiology KW - X Chromosome KW - XIST non-coding RNA N1 - Animated audio-visual presentation with synchronized narration; Title from title frames; Contents: X chromosome inactivation -- The X inactivation centre (Xic) -- Key role of the Xist locus -- Towards an understanding of Xist gene regulation in early mouse development -- Mechanisms regulating Xist RNA localisation within the inactive X chromosome territory -- Chromatin modification and gene silencing by Xist RNA; Access restricted to subscribers UR - https://hstalks.com/bs/3341/ UR - https://hstalks.com/bs/p/18/ ER -