TY - ADVS AU - Shyr,Yu TI - Adaptive clinical trials: conclusion and future directions T2 - Adaptive clinical trial design, PY - 2017/// CY - London PB - Henry Stewart Talks KW - Biochemical markers KW - Clinical trials KW - Design KW - Statistical methods KW - Drug development KW - Biomarkers, Pharmacological KW - Clinical Trials, Phase I as Topic KW - methods KW - Clinical Trials, Phase II as Topic KW - Clinical Trials, Phase III as Topic KW - Drug Evaluation, Preclinical KW - Drug Evaluation KW - Endpoint Determination KW - Randomized Controlled Trials as Topic KW - Research Design N1 - Animated audio-visual presentation with synchronized narration; Title from title frames; Contents: Definition of an adaptive clinical trial -- Three major types of trials -- Three types of clinical endpoints -- Biomarker-adaptive clinical trials design -- Recently FDA approved drugs -- Prognostic marker -- Predictive marker -- Enrichment designs -- Biomarker-stratified design -- Randomized hybrid design -- Umbrella and basket trials -- Examples of phase I, II, and III trials; Access restricted to subscribers UR - https://hstalks.com/bs/3568/ UR - https://hstalks.com/bs/p/1021/ ER -