TY - ADVS AU - Ferré,Sergi TI - Pre-coupling of receptor oligomers and signaling molecules: challenging classical pharmacology T2 - G Protein-Coupled Receptors (GPCRs) signaling in health and disease, PY - 2019/// CY - London PB - Henry Stewart Talks KW - Cellular signal transduction KW - Drug development KW - G proteins KW - Receptors KW - Adenylyl Cyclases KW - Pharmaceutical Preparations KW - Receptors, Dopamine D2 KW - Receptors, G-Protein-Coupled KW - chemistry KW - metabolism KW - Signal Transduction N1 - Animated audio-visual presentation with synchronized narration; Title from title frames; Contents: Pre-coupling of GPCRs with G proteins and adenylyl cyclase -- GPCR homomers and heteromers -- GPCR oligomer-dependent allosteric modulations between orthosteric ligands -- GPCR heteromer-dependent interactions at the adenylyl cyclase level -- The striatal adenosine A2A-dopamine D2 receptor heterotetramer; Access restricted to subscribers UR - https://hstalks.com/bs/3908/ UR - https://hstalks.com/bs/p/1083/ ER -