TY - ADVS AU - Settembre,Carmine TI - Autophagy dysfunction in lysosomal storage disorders T2 - Autophagy and lysosomal storage diseases, PY - 2019/// CY - London PB - Henry Stewart Talks KW - Cell death KW - Lysosomal storage disorders KW - Lysosomes KW - Autophagy KW - drug effects KW - physiology KW - Lysosomal Storage Diseases KW - metabolism KW - Mechanistic Target of Rapamycin Complex 1 N1 - Animated audio-visual presentation with synchronized narration; Title from title frames; Contents: Overview of the lysosome and autophagy -- Lysosomal storage disorders (LSDs) -- Lysosomal vacuolization -- Accumulation of LC3+ vesicles -- Studying co-localization of Lamp1 with LC3 and p62 -- LC3-tandem assay to study AV-lysosome fusion -- mTORC1 inhibitors and AV-lysosome fusion -- Pharmacological modulation of autophagy; Access restricted to subscribers UR - https://hstalks.com/bs/4103/ UR - https://hstalks.com/bs/p/1041/ ER -