TY - ADVS AU - Cragg,Mark TI - Monoclonal antibodies in haemato-oncology T2 - Monoclonal antibodies as therapeutic agents : fundamentals, therapeutic applications and latest advances, PY - 2020/// CY - London PB - Henry Stewart Talks KW - Antineoplastic agents KW - Lymphoma KW - Chemotherapy KW - Monoclonal antibodies KW - Antibodies, Monoclonal KW - therapeutic use KW - Antineoplastic Agents KW - pharmacology KW - Antineoplastic Agents, Immunological KW - B-Lymphocytes KW - Immunity, Cellular KW - drug therapy KW - Macrophages KW - obinutuzumab KW - Receptors, IgG KW - drug effects KW - metabolism KW - Rituximab KW - phamacology N1 - Animated audio-visual presentation with synchronized narration; Title from title frames; Contents: Introduction to the development and clinical use of monoclonal antibodies (mAb) in haemato-oncology -- Currently approved mAb for treating cancer -- Direct targeting antibodies -- Rituximab -- Fc gamma receptors (FcgR) as key mediators of cellular immunity -- Macrophages as key effector cells -- B cell deletion as a paradigm for mAb effects -- Type I versus Type II antibodies -- Obinutuzumab -- Immunomodulatory mAb -- Combinations between direct targeting and immunomodulatory mAb; Access restricted to subscribers UR - https://hstalks.com/bs/4266/ UR - https://hstalks.com/bs/p/30/ ER -