TY - ADVS AU - Kieft,Jeffrey TI - Factor independent initiation of protein synthesis by IRES RNAs T2 - The mechanisms of ribosome function : insights into protein synthesis, PY - 2020/// CY - London PB - Henry Stewart Talks KW - Eukaryotic cells KW - Genetics KW - Genetic translation KW - Protein biosynthesis KW - Ribosomes KW - Eukaryota KW - genetics KW - Internal Ribosome Entry Sites KW - Molecular Mimicry KW - Protein Biosynthesis KW - Ribosomal proteins KW - metabolism N1 - Animated audio-visual presentation with synchronized narration; Title from title frames; Updated version of a talk first published in 2008; Contents: Translation initiation in eukaryotes: two pathways -- IRES-driven translation -- Types of IRESes -- IRES manipulation of ribosomes -- Folding and structure of the IGR IRESes -- IRES interactions with the ribosome and molecular mimicry -- New IRES mechanistic models -- Towards an understanding of more complex IRESes; Access restricted to subscribers UR - https://hstalks.com/bs/805/ UR - https://hstalks.com/bs/p/285/ ER -