TY - ADVS AU - Paul,Thomas A. TI - Cancer-specific epigenetic alterations as investigated from a pharmaceutical perspective T2 - The biomedical & life sciences collection, PY - 2021/// CY - London PB - Henry Stewart Talks KW - Antineoplastic agents KW - Development KW - Cancer KW - Genetic aspects KW - Epigenesis KW - Antineoplastic Agents KW - pharmacology KW - Chromatin Assembly and Disassembly KW - genetics KW - Epigenesis, Genetic KW - Histone Deacetylase Inhibitors KW - Neoplasms KW - drug therapy N1 - Animated audio-visual presentation with synchronized narration; Title from title frames; Contents: Chromatin dysregulation in cancer -- Features of epigenetic information in cells -- Mutated chromatin regulatory factors as tumor drivers -- Therapeutic rationale for the use of epigenetic drugs in oncology -- First generation epigenetic drugs: DNMT and HDAC inhibitors -- Novel therapeutic discoveries in oncology -- Biomarkers for patient selection; Access restricted to subscribers UR - https://hstalks.com/bs/4491/ ER -