TY  - SOUND
AU  - Yamauchi,Yohei
TI  - The role of Neuropilin-1 as a SARS-CoV-2-specific endocytosis potentiator
T2  - Interviews on Covid-19,
PY  - 2021///
CY  - London
PB  - Henry Stewart Talks
KW  - Cell receptors
KW  - Coronaviruses
KW  - COVID-19 (Disease)
KW  - Research
KW  - Drug development
KW  - Host-virus relationships
KW  - Angiotensin-Converting Enzyme 2
KW  - Antiviral Agents
KW  - Betacoronavirus
KW  - physiology
KW  - Coronavirus infections
KW  - COVID-19
KW  - virology
KW  - Endocytosis
KW  - Epithelium
KW  - Lung
KW  - Neuropilin-1
KW  - SARS-CoV-2
KW  - Spike Glycoprotein, Coronavirus
KW  - metabolism
KW  - Virus Internalization
N1  - Audio interview; Title from title frames; Contents: Differences in the structure and biological properties of SARS-CoV-2 Spike proteins compared to those of other coronaviruses (including SARS) -- The distinct profile of the distribution of SARS-CoV-2-infected cells, particularly in lung and epithelial tissue, compared to other coronaviruses -- SARS-CoV-2's Spike protein sequence grants it the unique ability to interact with Neuropilin-1, in addition to ACE2 -- Role of Neuropilin-1, a cell-surface co-receptor, in facilitating mechanisms of SARS-CoV-2 entry into cells -- Current understanding of the influence of Neuropilin-1 on the development of COVID-19 and on disease progression -- The potential of developing SARS-CoV-2-specific antiviral drugs targeting Neuropilin-1; Access restricted to subscribers
UR  - https://hstalks.com/bs/4576/
UR  - https://hstalks.com/bs/p/1060/
ER  -