TY - ADVS AU - Cullen,Bryan R. TI - Viral epitranscriptomics T2 - Periodic reports : advances in clinical interventions and research platforms, PY - 2021/// CY - London PB - Henry Stewart Talks KW - HIV (Viruses) KW - Genetic aspects KW - Messenger RNA KW - Adenosine KW - analogs & derivatives KW - Cytidine KW - HIV-1 KW - genetics KW - Methylation KW - N6-methyladenosine (m6A) KW - RNA Processing, Post-Transcriptional KW - RNA Stability KW - RNA Viruses KW - RNA, Messenger KW - RNA, Viral N1 - Animated audio-visual presentation with synchronized narration; Title from title frames; Contents: Epitranscriptomic modifications (m6A, m5C and ac4c modifications) -- mRNA epitranscriptomic modification -- Loss of m6A modifiers and IVA replication -- m6A modifiers: YTHDF proteins and METTL3 -- Epitranscriptomic modifications in HIV-1 -- m5C modifiers: NSUN2 -- ac4c modifiers: NAT10 -- m6A and ac4c increase viral mRNA stability while m5C increases viral mRNA translation; Access restricted to subscribers UR - https://hstalks.com/bs/4510/ UR - https://hstalks.com/bs/p/1048/ ER -