TY - ADVS AU - Kolb,Peter TI - Drugging conformational states of GPCRs T2 - G Protein-Coupled Receptors (GPCRs) signaling in health and disease, PY - 2021/// CY - London PB - Henry Stewart Talks KW - Drugs KW - Design KW - G proteins KW - Receptors KW - Molecular structure KW - Computer simulation KW - Drug Design KW - Ligands KW - Models, Molecular KW - Molecular Docking Simulation KW - Protein Conformation KW - Receptors, G-Protein-Coupled KW - chemistry N1 - Animated audio-visual presentation with synchronized narration; Title from title frames; Contents: Structure-based drug design -- GPCRs and their conformational spectrum -- Docking to find selective ligands and ligands with tailored efficacy -- Expanding chemical space to address different GPCR conformations; Access restricted to subscribers UR - https://hstalks.com/bs/4523/ UR - https://hstalks.com/bs/p/1083/ ER -