TY - ADVS AU - Hardy,John TI - A molecular understanding of Alzheimer's disease T2 - Neurodegenerative diseases : fundamentals, research methods, latest advances, PY - 2021/// CY - London PB - Henry Stewart Talks KW - Alzheimer's disease KW - Genetic aspects KW - Molecular aspects KW - Nervous system KW - Degeneration KW - Alzheimer Disease KW - genetics KW - pathology KW - Amyloid KW - Amyloidogenic Proteins KW - Frontotemporal Dementia KW - Mutation KW - Neurodegenerative Diseases KW - Pick Disease of the Brain KW - Presenilins N1 - Animated audio-visual presentation with synchronized narration; Title from title frames; Updated version of a talk first published in 2007; Contents: Usefulness of genetics in understanding AD -- Pathology of diseases -- Amyloid protein -- Genetic maps -- Mechanism of late onset Alzheimer's -- Role of presenilin in amyloid pathology -- Tau and frontotemporal dementia -- Tau splice site mutations -- Pathways to neurodegeneration; Access restricted to subscribers UR - https://hstalks.com/bs/226/ UR - https://hstalks.com/bs/p/31/ ER -