TY - ADVS AU - Massagué,Joan TI - SMAD phosphorylation and the TGF-beta pathway T2 - Protein phosphorylation, PY - 2010/// CY - London PB - Henry Stewart Talks KW - Cancer KW - Molecular aspects KW - Cellular signal transduction KW - Phosphorylation KW - Proteins KW - Metabolism KW - Transforming growth factors-beta KW - Cell Transformation, Neoplastic KW - Embryonic Development KW - Homeostasis KW - Neoplasms KW - metabolism KW - Protein Serine-Threonine Kinases KW - Receptors, Transforming Growth Factor beta KW - Signal Transduction KW - physiology KW - Smad Proteins KW - Transforming Growth Factor beta N1 - Animated audio-visual presentation with synchronized narration; Title from title frames; Contents: The TGFb family as a paradigm of multifunctional cytokines -- TGFb controlling embryo development and tissue homeostasis -- TGFb receptor serine/threonine kinases -- SMADs as central TGFb signal transducers and transcriptional mediators -- Logic and organization of TGFb signaling processes -- TGFb pathway regulation and integration in the cell -- TGFb pathway disruption in heritable disorders and cancer; Access restricted to subscribers UR - https://hstalks.com/bs/1892/ UR - https://hstalks.com/bs/p/1079/ UR - https://hstalks.com/bs/p/531/ ER -