TY  - ADVS
AU  - Gold,Larry
TI  - The proteomic revolution
T2  - Biomarkers : the path forward to highly sensitive and specific molecular diagnostics,
PY  - 2022///
CY  - London
PB  - Henry Stewart Talks
KW  - Biochemical markers
KW  - Cancer
KW  - Diagnosis
KW  - Molecular diagnosis
KW  - Proteins
KW  - Analysis
KW  - Proteomics
KW  - Methodology
KW  - Biomarkers
KW  - Cardiovascular Diseases
KW  - DNA
KW  - Heart Disease Risk Factors
KW  - Lung Neoplasms
KW  - diagnosis
KW  - Mesothelioma
KW  - Molecular Diagnostic Techniques
KW  - Pancreatic Neoplasms
KW  - Pathology, Molecular
KW  - Protein Binding
KW  - analysis
KW  - methods
KW  - Risk Factors
KW  - Term Birth
N1  - Animated audio-visual presentation with synchronized narration; Title from title frames; Updated version of a talk first published in 2012; Contents: The proteomic revolution -- Proteomics is the best measure of phenotype (biomarkers) -- Slow Off-rate Modified Aptamers (SOMAmers) are breakthrough protein binding reagents -- SOMAmers are multiplexed to perform SOMAscan assay, which measures >1000 proteins in small sample volumes using DNA measurement tools to identify and quantify proteins bound by SOMAmers -- Applications of SOMAscan to date include finding valid protein biomarkers for lung cancer, cardiovascular risk, pre-term birth, pancreatic cancer, mesothelioma, and many other diseases and conditions -- Ability to do comprehensive longitudinal proteomics studies will revolutionize medicine; Access restricted to subscribers
UR  - https://hstalks.com/bs/2394/
UR  - https://hstalks.com/bs/p/666/
ER  -