TY - BOOK AU - Lansky,Ephraim P. AU - Lansky,Shifra AU - Paavilainen,Helena M. TI - Harmal: the genus Peganum T2 - Traditional herbal medicines for modern times SN - 9781315118758 AV - QK495.Z9 L36 2017 U1 - 583.79 PY - 2017/// CY - Boca Raton PB - Taylor & Francis KW - Peganum harmala N1 - Includes bibliographical references; chapter 1 Introduction; Ephraim Shmaya Lansky Shifra Lansky Helena Maaria Paavilainen --; chapter 2 The Genus Peganum; Ephraim Shmaya Lansky Shifra Lansky Helena Maaria Paavilainen --; chapter 3 Entheogenesis and Entheogenic Employment of Harmal; Ephraim Shmaya Lansky Shifra Lansky Helena Maaria Paavilainen --; chapter 4 Overview of Employment of Harmal in Traditional Iranian Medicine; Ephraim Shmaya Lansky Shifra Lansky Helena Maaria Paavilainen --; chapter 5 Harmal as Anticancer Agent in Traditional Chinese and Iranian Medicine; Ephraim Shmaya Lansky Shifra Lansky Helena Maaria Paavilainen --; chapter 6 Phytochemistry of Harmal; Ephraim Shmaya Lansky Shifra Lansky Helena Maaria Paavilainen --; chapter 7 Modern Pharmacognostic Investigation of Harmal; Ephraim Shmaya Lansky Shifra Lansky Helena Maaria Paavilainen --; chapter 8 Clinical Anticancer Use of Harmal: Two Cases; Ephraim Shmaya Lansky Shifra Lansky Helena Maaria Paavilainen --; chapter 9 Lympho-Neuric Syncytium and the Somatodelic Hypothesis; Ephraim Shmaya Lansky Shifra Lansky Helena Maaria Paavilainen --; chapter 10 Conclusion; Ephraim Shmaya Lansky Shifra Lansky Helena Maaria Paavilainen N2 - "Harmal: The Genus Peganum is an in-depth treatment of one of the most commanding plants in the botanical kingdom. Humble in appearance, modest in its needs, Peganum harmala has been venerated for millennia as a Deity-manifesting entheogen and a powerful medicine. This book traverses harmal's medicinal chemistry, its possible role in the origins of religion, and its employment from ancient times to the present in the therapy of patients suffering from infections, infestations, metabolic derangements, neurological degeneration, visual weakness, and cancer. Its peculiar indolic compounds, known as harmala alkaloids, are now appreciated as exerting profound effects on the mind and on the body. These effects are the result of the alkaloids' interactions with, and binding to, serotonin receptors on the cell surfaces of neurons in the brain and lymphocytes in the blood, the latter constituting the diffuse structural basis of the immune system. This biphasic modulation by harmala alkaloids has led to a novel pharmacologic re-visioning presented herein for the first time, the concept of a "lymphoneuric syncytium" and its possible long term tuning via "somatodelic" as well as "psychedelic" effects.The scientific rationale underlying the use of harmal in the medicines of the past and the healing technologies of our future is developed through exhaustive and meticulous explorations in both ethnopharmacology and modern phytochemistry. The presentation is enhanced through appraisals of the effects of harmal in two clinical cancer case scenarios, and of intentional inebriation and "provings" by one of the authors and a psychiatric colleague. The noted and esteemed botanically-trained physician Dr. Andrew Weil states in his Preface that this "monumental" volume will become the standard reference work in the field. Harmal: The Genus Peganum will be an invaluable addition to the personal libraries of professional pharmacognosists, botanists, physicians, psychologists, neuroscientists, and all persons interested in the interrelationship of consciousness, medicine, and coevolution. "--Provided by publisher UR - https://www.taylorfrancis.com/books/9781315118758 ER -