Signaling by innate immune receptors [electronic resource] / Michael Karin.
Material type:
FilmSeries: Henry Stewart talksBiomedical & life sciences collection. Innate immunity : host recognition and response in health and disease: Publisher: London : Henry Stewart Talks, 2009Description: 1 online resource (1 streaming video file (38 min.) : color, sound)Subject(s): Immunity, InnateOnline resources: Click here to access online | Series Animated audio-visual presentation with synchronized narration.
Title from title frames.
Contents: Understanding how receptors involved in the detection of infection (TLRs and NLRs) and inflammation (TNFRs) mediated their biological effects -- The activation of innate immune responses depends on recognition of infectious organisms (bacteria, fungi, viruses, etc.) by specialized pattern recognition receptors that include the large families of membrane-associated TLRs and cytosolic NLRs -- Signaling mechanisms used by TLRs and NLRs, as well as by TNFRs that respond to pro-inflammatory cytokines -- Their biological effects include the production of cytokines, chemokines, anti-microbial peptides and enzymes that generate inflammatory mediators and reactive oxygen.
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Mode of access: World Wide Web.