Translocational applications of cardiovascular genomics [electronic resource] : opportunities and challenges / Aroon Hingorani.
Material type:
FilmSeries: Henry Stewart talksBiomedical & life sciences collection. Genetics of cardiovascular disease: Publisher: London : Henry Stewart Talks, 2008Description: 1 online resource (1 streaming video file (33 min.) : color, sound)Subject(s): Cardiovascular Diseases -- geneticsOnline resources: Click here to access online | Series Animated audio-visual presentation with synchronized narration.
Title from title frames.
Contents: Ischaemic heart disease -- Valvular heart disease -- Heart muscle disease -- Monogenic form of common disorder -- Single gene disorders and cardiovascular disease -- Mutation both necessary and sufficient to lead to disease -- Genetic basis of the common form of CHD -- Polygenic form of common disorder -- Complex disorders -- Study design -- Candidate genes or whole genome -- Genome-wide association studies -- A new dawn for genetics of complex disorders and traits -- Relationship between allele frequency and effect size -- Genetic architecture of common disease -- Translation of genomic discoveries -- Potential advantages of genetic tests -- Predictive genetic screening for CHD -- Low penetrance polymorphisms -- Multiple risk alleles -- Why genetic testing might perform poorly as a discriminatory test -- Genotype and prediction of CHD -- Using genotype to gain insight into the causes of CHD -- Unique properties of genotype.
Access restricted to subscribers.
Mode of access: World Wide Web.