Spinal drug delivery [electronic resource] : technology, biology and toxicology / Tony L. Yaksh.
Material type:
FilmSeries: Henry Stewart talksBiomedical & life sciences collection. Pain and the control of pain : pain transmission, regulation and management: Publisher: London : Henry Stewart Talks, 2009Description: 1 online resource (1 streaming video file (48 min.) : color, sound)Subject(s): Anesthesia, Spinal | Pain -- drug therapy | Pain -- prevention & control | Pain -- therapyOnline resources: Click here to access online | Series Animated audio-visual presentation with synchronized narration.
Title from title frames.
Contents: Pain: concepts and early anatomy -- Role of sensory nerves and spinal cord -- Enabling technology for spinal anesthesia -- Rapid evolution of spinal anesthetic delivery in the US -- Early appreciation of risks of spinal anesthesia -- Modulation of spinal processing -- Targeting drugs at spinal function -- Other systems which regulate spinal afferent transmission -- Pain selectively diminished by spinal opioids -- Spinal mu/delta opioid action -- Spinal analgesics: animal and human pain -- Safety of spinal drugs -- Early safety issues with spinal anesthetic -- Classes of spinal toxicity -- Intrathecal lidocaine and toxicity -- Spinal toxicity: root, parenchyma, meningeal -- Human intrathecal morphine: granuloma -- IT morphine and granulomas concentration vs. dose -- Future and neuraxial drug delivery.
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Mode of access: World Wide Web.