Animal models to explore cardiovascular disease [electronic resource] / Martin Merkel.
Material type:
FilmSeries: Henry Stewart talksBiomedical & life sciences collection. Genetics of cardiovascular disease: Publisher: London : Henry Stewart Talks, 2008Description: 1 online resource (1 streaming video file (39 min.) : color, sound)Subject(s): Atherosclerosis | Cardiovascular Diseases -- geneticsOnline resources: Click here to access online | Series Animated audio-visual presentation with synchronized narration.
Title from title frames.
Contents: Atherosclerosis is a complex disease involving several different molecular and cellular mechanisms in its pathogenesis -- For its experimental investigation, usually higher animals as mammals need to be employed -- Here, the animal models currently used in atherosclerotic research are reviewed und their respective advantages and disadvantages are depicted -- Use of inbred mouse strains and different genetically modified mice -- The main disparities between mouse and human lipid metabolism -- Considerations and techniques to create useful animal models.
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Mode of access: World Wide Web.