Use of DNA pooling in large-scale association studies [electronic resource] / Pak Sham.
Material type:
FilmSeries: Henry Stewart talksBiomedical & life sciences collection. Genetic epidemiology I : fundamentals, theory, practice and latest developments: Publisher: London : Henry Stewart Talks, 2004Description: 1 online resource (1 streaming video file (30 min.) : color, sound)Subject(s): Genetic Predisposition to Disease -- epidemiologyOnline resources: Click here to access online | Series Animated audio-visual presentation with synchronized narration.
Title from title frames.
Contents: Principles of DNA pooling -- The cost benefit -- Getting the quantification right -- SNaPshot -- Estimating and incorporating measurement error -- Consequences of differential amplification -- Pool construction vs. genotyping errors -- Determining optimal design -- Family designs -- Stratified designs -- Design for quantitative traits -- Methods for statistical analysis -- Case study: ADHD -- Approaches to haplotype analysis in DNA pooling -- Recommendations.
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Mode of access: World Wide Web.