Nuclear receptors superfamily [electronic resource] : structural insights into function / Dino Moras.
Material type:
FilmSeries: Henry Stewart talksBiomedical & life sciences collection. World of hormones : molecular and physiological insights: Publisher: London : Henry Stewart Talks, 2007Description: 1 online resource (1 streaming video file (44 min.) : color, sound)Subject(s): Hormones | Receptors, Cytoplasmic and NuclearOnline resources: Click here to access online | Series Animated audio-visual presentation with synchronized narration.
Title from title frames.
Contents: Signal transduction and transcriptional regulation -- Cofactor binding and transcriptional activation -- The modular organization of nuclear hormone receptors -- The DNA binding domain -- The ligand binding domain -- Sequence/structure to function -- The oligomeric state -- Allosteric control through post-translational modifications -- Communication pathways in NRs -- Ligand binding: specificity and adaptability -- The retinoid receptors: RXR and RAR -- Structural adaptability in the ligand-binding pocket of the ecdysone hormone receptor -- Binding to coactivators and corepressors: the signature motifs -- Ligand dependent (de)activation: agonists and antagonists -- Estrogen receptor -- The vitamin D receptor.
Access restricted to subscribers.
Mode of access: World Wide Web.