Blood brain barrier in health and disease [electronic resource] / Thomas P. Davis.
Material type:
FilmSeries: Henry Stewart talksBiomedical & life sciences collection. Blood-brain barrier : understanding the regulatory gatekeeper between brain and body: Publisher: London : Henry Stewart Talks, 2008Description: 1 online resource (1 streaming video file (62 min.) : color, sound)Subject(s): Blood-Brain Barrier | Brain Diseases -- therapy | BrainOnline resources: Click here to access online | Series Animated audio-visual presentation with synchronized narration.
Title from title frames.
Contents: The blood-brain barrier is not a static barrier -- The blood-brain barrier does inhibit drug delivery to the brain -- The blood-brain barrier is at the level of the endothelial cell cytoarchitecture that line all cerebral blood vessels in the brain -- The blood-brain barrier consists of a unique set of regulated proteins held together in a tight cytoarchitectural matrix to form a tight junction -- Stressors such as head injury, hypoxia, pain and diseases such as M.S, diabetes, Alzheimer's, cancer and stroke alter tight junction proteins of the blood-brain barrier leading to a "leak" and a loss of integrity -- Understanding what controls the integrity of the blood-brain barrier is critical if we are to understand how to treat the diseases of the brain.
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Mode of access: World Wide Web.