Antibiotic inhibition of ribosome function [electronic resource] / Daniel N. Wilson.
Material type:
FilmSeries: Henry Stewart talksBiomedical & life sciences collection. Mechanisms of ribosome function : insights into protein synthesis: Publisher: London : Henry Stewart Talks, 2008Description: 1 online resource (1 streaming video file (35 min.) : color, sound)Subject(s): Protein Biosynthesis | Ribosomal Proteins | RibosomesOnline resources: Click here to access online | Series Animated audio-visual presentation with synchronized narration.
Title from title frames.
Contents: Overview of antibiotics that target the ribosome -- Different mechanisms by which translation initiation inhibitors, such as kasugamycin and edeine, perturb initiator tRNA binding -- Structural insight into how the thiopeptide class of antibiotics, such as thiostrepton and micrococcin, inhibit stable binding of translation factors, such as EF-G, to the ribosome -- Mechanism by which drugs, such as chloramphenicol and macrolides inhibit the peptidyltransferase reaction -- How species specific differences in antibiotic interaction sites between different organisms can have a dramatic influence on drug binding.
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Mode of access: World Wide Web.