The endoplasmic reticulum as a most efficient antibody factory [electronic resource] / Roberto Sitia.
Material type:
FilmSeries: Henry Stewart talksBiomedical & life sciences collection. Endoplasmic reticulum : fundamentals and role in disease: Publisher: London : Henry Stewart Talks, 2007Description: 1 online resource (1 streaming video file (47 min.) : color, sound)Subject(s): Endoplasmic ReticulumOnline resources: Click here to access online | Series Animated audio-visual presentation with synchronized narration.
Title from title frames.
Contents: Studies on the synthesis, assembly and secretion of antibodies during B cell development reveal fundamental properties of the endoplasmic reticulum as a protein factory -- How do cells regulate the formation, isomerisation and reduction of disulfide bonds? -- How do plasma cells manage to secrete massive amounts of antibodies? -- Is antibody production somehow controling plasma cell lifespan? -- Answers to these questions have profound implications in biotechnology and medicine, as they may help design better bioreactors for the production of recombinant proteins and better therapies for multiple myeloma and other secretory tumors.
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Mode of access: World Wide Web.