Protein aggregation, metals and oxidative stress in neurodegenerative diseases [electronic resource] / David Allsop.
Material type:
FilmSeries: Henry Stewart talksBiomedical & life sciences collection. Protein folding, aggregation and design : concepts, experiments, theories and mechanisms: Publisher: London : Henry Stewart Talks, 2007Description: 1 online resource (1 streaming video file (44 min.) : color, sound)Subject(s): Neurodegenerative Diseases | Protein Conformation | Protein Folding | ProteinsOnline resources: Click here to access online | Series Animated audio-visual presentation with synchronized narration.
Title from title frames.
Contents: Introduction to protein conformational brain diseases -- Alzheimer's disease, A-beta and tau -- A-beta oligomers and toxicity -- A-beta generates hydrogen peroxide -- Results from experiments using electron spin resonance spectroscopy -- Parkinson's disease -- Generation of hydrogen peroxide from alpha synuclein, toxic fragments of the prion protein and the familial British dementia peptide -- Early oligomers appear to generate hydrogen peroxide -- Huntington's disease -- Protein aggregates could be protective -- Potential common toxic pathway for these brain diseases.
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Mode of access: World Wide Web.