The molecular biology of the inositol trisphosphate receptor [electronic resource] / Randen Patterson.
Material type:![Film](/opac-tmpl/lib/famfamfam/VM.png)
Animated audio-visual presentation with synchronized narration.
Title from title frames.
Contents: Activation of the IP3-receptor (IP3R), a major endoplasmic Calcium release channel in many cells, is activated by the second messenger inositol 1,4,5-trisphosphate (IP3) -- The IP3R is unique in that it can integrate signals from numerous cellular pathways via a myriad of inputs which include nucleotide binding, phosphorylation, Calcium binding and protein-protein interactions -- A diverse range of cellular functions are modulated by the IP3R including contraction/excitation, secretion, gene expression, cell cycle, apoptosis and cellular growth -- The nodal properties of the IP3R and the mechanisms by which this occurs.
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Mode of access: World Wide Web.