Anti TNF therapy in rheumatoid arthritis [electronic resource] / Marc Feldmann.
Material type:
FilmSeries: Henry Stewart talksBiomedical & life sciences collection. Monoclonal antibodies as therapeutic agents : fundamentals, therapeutic applications and latest advances: Publisher: London : Henry Stewart Talks, 2007Description: 1 online resource (1 streaming video file (58 min.) : color, sound)Other title: Anti-TNF therapy in rheumatoid arthritisSubject(s): Antibodies, Monoclonal -- therapeutic use | Arthritis, Rheumatoid -- immunology | Arthritis, Rheumatoid -- therapy | Arthritis, Rheumatoid | Tumor Necrosis Factor-alpha -- therapeutic use | Tumor Necrosis Factor-alphaOnline resources: Click here to access online | Series Animated audio-visual presentation with synchronized narration.
Title from title frames.
Contents: Immunological basis of rheumatoid arthritis (RA) -- Up-regulated cytokine expression is of major importance in RA -- Analysis of the disordered regulation shows that TNF blockade restored normal cytokine and destructive molecule levels and thus defined TNF as a therapeutic target -- Animal models of arthritis -- Clinical trials -- TNF has major input into leucocyte recruitment, it is thus the body's fire alarm -- TNF blockade and Crohn's disease, ulcerative colitis, ankylosing spondylitis, psoriasis, psoriatic arthritis and juvenile RA -- This represents the first major use for monoclonal antibodies in chronic diseases.
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Mode of access: World Wide Web.