Genetic, environmental and other design issues relevant for pharmacogenetics studies [electronic resource] / Ridha Joober.
Material type:
FilmSeries: Henry Stewart talksBiomedical & life sciences collection. Psychopharmacogenetics : genetic factors influencing the kinetics and dynamics of psychotropic drugs: Publisher: London : Henry Stewart Talks, 2007Description: 1 online resource (1 streaming video file (45 min.) : color, sound)Subject(s): Pharmacogenetics | Psychopharmacology | Psychotropic DrugsOnline resources: Click here to access online | Series Animated audio-visual presentation with synchronized narration.
Title from title frames.
Contents: Definition of pharmacogenetics (PGx), pharmacokinetics and pharmacodynamics -- Modulation of PGx phenotypes -- Genetic factors play a role in determining the variability of PGx phenotypes -- Study design -- Genetic epidemiology -- Familial aggregation studies -- Twin and adoption studies -- Therapeutic response to psychotropic drugs -- Pharmaco-epidemiology and PGx phenotypes -- Animal models -- Balancing modest epidemiological evidence against biological pertinence -- Studying PGx phenotypes in relation to candidate genes -- Family-based vs. case control designs -- Observer effect -- Sampling bias -- Factors related to the subject.
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Mode of access: World Wide Web.