Endothelial cell apoptosis [electronic resource] / Richard Kolesnick.
Material type: FilmSeries: Henry Stewart talksBiomedical & life sciences collection. Apoptosis : fundamentals, pathways, clinical applications and role in disease: Publisher: London : Henry Stewart Talks, 2007Description: 1 online resource (1 streaming video file (49 min.) : color, sound)Subject(s): Apoptosis | Endothelial Cells | Neoplasms -- radiotherapyOnline resources: Click here to access online | SeriesAnimated audio-visual presentation with synchronized narration.
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Contents: Endothelial apoptosis -- Role in tumor response to radiation therapy -- Tissue damage results from depletion of stem cells and cells with clonogenic capacity -- Radiation targets the DNA leading to reproductive (mitosis-associated) or apoptotic cell death -- Modifications of DNA damage recognition and repair pathways determine the level of tissue sensitivity to radiation -- Sphingomyelin -- Ceramide -- GI tract and bone marrow: very radiation responsive -- Growth patterns of tumors -- The two-target model for single-dose radiotherapy of experimental tumors -- Engaging the vascular component of tumor response to radiation.
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Mode of access: World Wide Web.