Mammalian microRNP assembly & function [electronic resource] / Zissimos Mourelatos.
Material type:
FilmSeries: Henry Stewart talksBiomedical & life sciences collection. RNA interference : principles and applications: Publisher: London : Henry Stewart Talks, 2007Description: 1 online resource (1 streaming video file (26 min.) : color, sound)Other title: Mammalian microRNP assembly and functionSubject(s): Messenger RNA | MicroRNAs | RNA Interference | RNA, Messenger | RNA, Small InterferingOnline resources: Click here to access online | Series Animated audio-visual presentation with synchronized narration.
Title from title frames.
Contents: miRNAs and RNA interference, nuclear biogenesis and cytoplasmic processing -- siRNA biogenesis and assembly -- Silencing by target mRNA cleavage and "translational repression" -- RISC assembly in flies -- RISC activity and Dicer -- Model of the miRNA assembly pathway in humans -- Prediction of miRNA targets -- Compensatory mutations: rescue -- How miRNAs and siRNAs recognize their targets -- Additional principles of target RNA recognition by miRNAs and siRNAs.
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Mode of access: World Wide Web.