Epigenetic control by histone methylation [electronic resource] / Thomas Jenuwein.
Material type: FilmSeries: Henry Stewart talksBiomedical & life sciences collection. Epigenetics : concepts, theories, paradigms and mechanisms: Publisher: London : Henry Stewart Talks, 2007Description: 1 online resource (1 streaming video file (68 min.) : color, sound)Subject(s): Epigenesis | Histones | Methylation | Chromatin | Embryonic Stem Cells | Epigenesis, Genetic | Histone-Lysine N-Methyltransferase | Histones -- metabolism | Lysine -- metabolism | Methylation | Neoplasms -- genetics | Nuclear Reprogramming | Stem CellsOnline resources: Click here to access online | SeriesAnimated audio-visual presentation with synchronized narration.
Title from title frames.
Contents: The diversity of covalent histone tail modifications for imparting epigenetic information -- Observations of robust histone modifications at silent chromatin regions -- The representation of repressive histone marks as indications of epigenetic plasticity in different cells -- Analysis of the profiles of normal and aberrant histone lysine methylation patterns, as they occur during the transition of an embryonic to a differentiated cell or in controlled self-renewal vs. pro-neoplastic or metastatic conditions -- Elucidation of these histone modification patterns for novel advances in stem cell research, nuclear reprogramming and cancer.
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Mode of access: World Wide Web.