Eosinophils [electronic resource] / Tim Williams.
Material type:
FilmSeries: Henry Stewart talksBiomedical & life sciences collection. Innate immunity : host recognition and response in health and disease: Publisher: London : Henry Stewart Talks, 2009Description: 1 online resource (1 streaming video file (42 min.) : color, sound)Subject(s): Eosinophils | Immunity, InnateOnline resources: Click here to access online | Series Animated audio-visual presentation with synchonized narration.
Title from title frames.
Contents: White blood cell containing granules staining pink with eosin and a bilobed nucleus -- Specialised for defence against worm infection -- Accumulate in high numbers in lungs of allergic asthmatic patients -- Also involved in hay fever, allergic eczema etc -- Induce tissue damage and organ dysfunction when inappropriately activated -- Interleukin-5 (IL-5) important for eosinophil production in bone marrow -- Anti-IL-5 antibodies suppress circulating eosinophil numbers -- Eotaxin is a chemoattractant protein involved in recruiting eosinophils to the lung -- Small molecule antagonists have been developed to block the Eotaxin receptor, CCR3, as potential therapeutic compounds.
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Mode of access: World Wide Web.