Drug induced liver injury [electronic resource] : a clinical perspective / Victor J. Navarro.
Material type: FilmSeries: Henry Stewart talksBiomedical & life sciences collection. Non-clinical testing for toxicity of pharmaceuticals: Publisher: London : Henry Stewart Talks, 2009Description: 1 online resource (1 streaming video file (38 min.) : color, sound)Subject(s): Drug Toxicity | Toxicity TestsOnline resources: Click here to access online | SeriesAnimated audio-visual presentation with synchonized narration.
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Contents: Definition of drug induced liver injury (DILI) -- Types and mechanisms of DILI -- Safety withdrawals -- Signals of DILI in drug development -- Epidemiology of DILI -- Clinical patterns -- Hepatocellular liver injury -- Cholestatic liver injury -- What comprises liver injury? -- Adaptation to injury -- Toxicity grading in clinical trials -- Jaundice -- Common signatures of DILI -- Susceptibility factors for DILI -- Key elements in diagnosis -- Causality assessment tools -- Management of DILI -- Monitoring in clinical practice.
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Mode of access: World Wide Web.