From CagA to CagA [electronic resource] : the metamorphoses of the Helicobacter pylori's cytotoxin-associated gene A into the cancer-associated gene A / Antonello Covacci.
Material type:
FilmSeries: Henry Stewart talksBiomedical & life sciences collection. Molecular basis of bacterial Infection: Publisher: London : Henry Stewart Talks, 2010Description: 1 online resource (1 streaming video file (32 min.) : color, sound)Subject(s): cagA protein, Helicobacter pylori | NeoplasmsOnline resources: Click here to access online | Series Animated audio-visual presentation with synchronized narration.
Title from title frames.
Contents: Helicobacter pylori: a chronic pathogen with lifelong association with the host -- The cag pathogenicity island encoding the Type IV secretion system and the CagA effector molecule -- CagA is translocated into the host cells and is tyrosine-phosphorylated by the c-Src kinase -- CagA affects the host cell terminal differentiation program -- CagA is associated with tumorigenic conversion acting simultaneously on two major pathways.
Access restricted to subscribers.
Mode of access: World Wide Web.