Astrocyte control of cerebral blood vessels [electronic resource] / Brian A. MacVicar.
Material type:
FilmSeries: Henry Stewart talksBiomedical & life sciences collection: Publisher: London : Henry Stewart Talks, 2010Description: 1 online resource (1 streaming video file (47 min.) : color, sound)Subject(s): Astrocytes -- metabolism | Brain -- blood supply | Brain -- metabolism | Vasocontriction -- physiology | Vasodilation -- physiologyOnline resources: Click here to access online Animated audio-visual presentation with synchronized narration.
Title from title frames.
Contents: The regulation of the blood supply of the brain -- Functions of astrocytes -- Astrocytes all have endfeet -- Astrocyte endfeet enwrap all cerebral blood vessels -- The modulators of cerebral blood flow -- Astrocyte calcium waves cause vasoconstriction -- Astrocytes and vascular dynamics -- Functional impact of astrocyte induced constrictions -- Dilation is more complicated -- Can changing levels of O2 and lactate modify vasculature control by astrocytes? -- Tissue pO2 levels -- Complex regulation of dilation by metabolism -- Changing oxygen levels -- Astrocytes express both cyclooxygenase -1 and -2 -- Prostaglandin transporters -- Is there a relationship between lactate and PGE2? -- Why are vasoconstrictions not observed in low O2? -- Brain metabolic state dictates the polarity of astrocyte control over the cerebrovasculature.
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Mode of access: World Wide Web.