Serine kinases and T lymphocyte biology [electronic resource] / Doreen Cantrell.
Material type:![Film](/opac-tmpl/lib/famfamfam/VM.png)
Animated audio-visual presentation with synchronized narration.
Title from title frames.
Contents: T cell development and function -- T cell activation -- Serine kinase networks -- T cell phosphoproteome -- Kinases active in CTL -- Functions of the CTL phosphoproteins -- PKB signal transduction -- PKB/Akt role in CTL -- Inhibition of PKB -- CCR7 and CD62L -- Homing ability in CTL -- PIP3 & PKB activation -- PTEN deletion/down-regulation effect -- PKB phosphorylates Foxo1 and Foxo3A -- Foxo and CD62L & CCR7 expression -- PKB cascade and KLF2 -- PKB controls T cell trafficking via Foxo.
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Mode of access: World Wide Web.